BOTOX® Cosmetic

How does it work?

BOTOX® Cosmetic works to block nerve impulses to injected muscles. As muscle contractions are reduced, so are the wrinkle lines of expression.

What is BOTOX® Cosmetic?

BOTOX® Cosmetic, also known as onabotulinumtoxinA, is a purified protein that is produced by the bacterium Clostridium botulinum. It is manufactured by Allergan, Inc., and was FDA approved for cosmetic use in the United States in 2002 to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in people 18 to 65 years of age. Off-label, it is commonly used by physicians to treat the horizontal forehead lines, the crow’s feet on the side of the eyes, the bunny lines of the nose, chin dimpling, and other areas.

Am I a Candidate for Botox Cosmetic?

Botox Cosmetic is administered in localized injections so it is suitable for a wide variety of patients. Ideal candidates for Botox Cosmetic include those who:

  • Are in good overall health
  • Are looking to make changes in appearance without having to undergo major surgery
  • Have facial wrinkles, either minor or major in areas that are injection sites for Botox Cosmetic
  • Are not pregnant or breastfeeding
  • Do not have any major illnesses or infections
  • Have realistic expectations for the procedure

What should I expect for my initial visit?

We set aside extra time for you to visit with the doctor, discuss your goals, concerns, and be carefully evaluated to determine your options. Should you decide to proceed with treatment, a small needle (30- to 32-gauge) will be delicately used to inject a few drops (0.01ml to 0.1ml) of reconstituted BOTOX® Cosmetic into muscle that causes the wrinkle. This eventually relaxes the muscle to reduce the creasing of overlying skin during facial expression. Over time, static wrinkle lines (the ones at rest) may relax and soften. BOTOX® relaxes muscle. It does not pull, nor does it fill the skin.

How long will it last?

BOTOX® treatment results typically last three months, though this may vary from three to six months depending on the individual. Ones muscle anatomy, muscle strength, size, skin quality and thickness, and physiology can affect the treatment outcome. It is recommended that you not be retreated in less than three months time.

BOTOX® temporarily affects the nerve endings. Nerve impulses that trigger muscle contraction are blocked until the nerve endings undergo repair and resume normal function. This does not affect sensation or your ability to feel in the area of treatment.

What should I expect after treatment?

It may take 7 to 10 days or longer (up to 30 days) for you to see maximum treatment results. Most people do not notice a significant difference the day after treatment. You may notice some muscle relaxation before this, but this will progress until the peak effect is reached.

With repeated treatments, the beneficial effects may last longer. With regular use, BOTOX® may reversibly reduce the size of treated muscle until you begin using it. This is known as disuse atrophy and occurs naturally when a muscle is not exercised. This helps keep wrinkles slightly more relaxed during facial expression. At rest, the wrinkle itself may soften over time, because treated muscles do not constantly crease the skin. In essence, this allows the skin to repair the wrinkle.

Is it safe?

The clinical use of BOTOX® is the result of more than 100 years of study into Botulinum Neurotoxin Type A (BoNTA). BOTOX® is one the world’s most widely-researched medicines with approximately 2,300 publications in peer-reviewed scientific and medical journals.

The amount of BOTOX® that is injected for cosmetic use is relatively small in comparison to the that which is typically used to treat patients suffering from debilitating medical conditions, such as severe neck muscle spasm, upper limb spasticity, and cerebral palsy. Although most other drugs you are likely to be familiar with are injected with ample quantity into muscle or vein to achieve therapeutic serum drug levels, only small amounts of BOTOX® are used to work locally around the sites they are injected into.

Since BOTOX® Cosmetic is designed to work locally, the chance of this spreading to unintended areas is generally confined to adjacent muscle. There has not been a confirmed serious case of spread of toxin effect away from the injection site when BOTOX® has been used at the recommended dose to treat chronic migraine, severe underarm sweating, blepharospasm, or strabismus.

BOTOX® should not be administered in women who are pregnant, breastfeeding, or in patients who are known to be allergic to the BOTOX®, its ingredients or to other botulinum toxin products such as Myoblock®, Dysport® or Xeomin®.

BOTOX® Cosmetic (onabotulinumtoxinA) for injection

Manufactured by: Allergan Pharmaceuticals Ireland
a subsidiary of: Allergan, Inc. 2525 Dupont Dr., Irvine, CA 92612

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Medication Guide BOTOX® | BOTOX® Cosmetic

Read the Medication Guide that comes with BOTOX® or BOTOX® Cosmetic before you start using it and each time it is given to you. There may be new information. This information does not take the place of talking with your doctor about your medical condition or your treatment. You should share this information with your family members and caregivers.

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Contact us today at (310) 375-9595 to schedule your consultation with Dr. Lum and Lumier Medical.